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Role of Procalcitonin in the Early Detection of Anastomotic Leaks After Esophagectomy


Joanna Sesti MD1*, Daniel Tenorio MD1, Jaimie Bell DNP1, Amber L Turner MPH2, Patrick Hilden MS6, Andrew B Nguyen MD1, Zubin M Bamboat MD4, Russell C Langan MD3 and Subroto Paul MD, MPH15

Department of Thoracic Surgery, RWJ Barnabas Health, West Orange, NJ

Correspondence to Author: Joanna Sesti


Anastomotic leaks are devastating complications after esophagectomy, and early diagnosis is crucial. We sought to assess the association between procalcitonin levels and anastomotic leaks in post esophagectomy patients. Procalcitonin (PCT) levels were prospectively collected on patients undergoing esophagectomy within our hospital system between postoperative days 1 and 11. All patients were evaluated for an anastomotic leak between postoperative day 4 and 9. The sensitivity, specificity, negative, and positive predictive values based on procalcitonin level were calculated.


Anastomotic Leak; Computer Tomography; Esophago-Gastro-Duodenoscopy; Fahrenheit; Negative predictive value; Procalcitonin; Positive Predictive Value; White blood cell


Joanna Sesti. Role of Procalcitonin in the Early Detection of Anastomotic Leaks After Esophagectomy. World Journal of Clinical Surgery 2020.

Journal Info

  • Journal Name: World Journal of Clinical Surgery
  • Impact Factor: 2.709**
  • ISSN: 2766-6182
  • DOI: 10.52338/wjsurgy
  • Short Name: WJCSR
  • Acceptance rate: 55%
  • Volume: 6 (2024)
  • Submission to acceptance: 25 days
  • Acceptance to publication: 10 days


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